Erciyes University - Info Package

Course unit title	Level of course unit	Course unit code	Type of course unit	Semester of course unit	Local credit	ECTS credit	Syllabus
RECOMBINANT DNA TECHNOLOGY AND BIOTECHNOLOGICAL DRUGS	Second cycle	EAK 536		1	8.00	8.00	Print

Description of course unit

Prerequisites and course requisities	No required
Language of instruction	Turkish
Coordinator	ASSOC. DR. Dilşad ONBAŞLI
Lecturer(s)	ASSOC. DR. Dilşad ONBAŞLI
Teaching assitant(s)	None
Mode of delivery	The emphasis of this course will be on theoretical information on the subject.
Course objective	Recombinant DNA technology is to provide information about basic approaches to the subject and examine the extensive recombinant DNA technology and its applications. Recombinant DNA technology is to reveal the role of the biological drug manufacturing processes.
Course description	Basic information, applications and end approaches for the recombinant DNA technology and drugs

Course contents

1	Introduction to recombinant DNA technology
2	The structure of the genetic material
3	Restriction endonucleases
4	Vectors
5	Manipulation of gene expression in prokaryotes and eukaryotes
6	Cloning
7	Exam
8	Definition of biological drugs
9	The production of proteins by recombinant DNA technology and glycoproteins
10	Antibodies and antigens, nucleic acids, "antisense oligonucleotides"
11	Blood coagulation factors, hormones, interferons, interleukins
12	Recombinant vaccine technology
13	Tumor necrosis factors, natural drugs and their semisynthetic derivatives
14	Biosimilars
15	Final Exam
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17
18
19
20

Learning outcomes of the course unit

1	Students will learn information about basic information for the recombinant DNA technology
2	Students will learn information about applications for the recombinant DNA technology
3	Students will learn information about the latest approaches for the recombinant DNA technology
4	Students will learn information about basic information for the recombinant drugs
5	Students will learn information about basic information applications for the recombinant drugs
6	Students will learn information about basic information the latest approaches for the recombinant drugs
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10

*Contribution level of the course unit to the key learning outcomes

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Number of stars refer to level of contribution from 1 (the least) to 5 (the most)

Planned learning activities, teaching methods and ECTS work load

	Quantity	Time (hour)	Quantity*Time (hour)
Lectures (face to face teaching)	14	3	42
Study hours out of classroom (study before and after the class)	10	4	40
Homework	2	16	32
Presentation / seminar	2	12	24
Quiz	0	0	0
Preparation for midterm exams	1	20	20
Midterm exams	1	1	1
Project (term paper)	0	0	0
Laboratuar	0	0	0
Field study	0	0	0
Preparation for final exam	1	28	28
Final exam	1	1	1
Research	0	0	0
Total work load			188
ECTS			7.50

Assessment methods and criteria

Evaluation during semester	Quantity	Percentage
Midterm exam	1	10
Quiz	0	0
Homework	2	30
Semester total		40
Contribution ratio of evaluation during semester to success		40
Contribution ratio of final exam to success		60
General total		100

Recommended and required reading

Textbook	None
Additional references	1-Glick, B. R. And Pasternak, J. J. ‘Molecular Biotechnology’, ASM Press 1994, Washington D.C. 2-Sambrook et al, 1993. Molecular Cloning. Cold Spring Harbor Laboratory Press. New York

Files related to the course unit