Course unit title Level of course unit Course unit code Type of course unit Semester of course unit Local credit ECTS credit Syllabus
PREPERATIVE SEPERATION TECHNIQUES FOR NATURAL PRODUCTS Third cycle EFG 611 1 8.00 8.00 Print
   
Description of course unit
Prerequisites and course requisities No
Language of instruction Turkish
Coordinator Assist. Prof. Dr. Perihan GÜRBÜZ
Lecturer(s) Assist. Prof. Dr. Perihan GÜRBÜZ
Teaching assitant(s) None
Mode of delivery Theoric
Course objective It gives information about the methods of obtaining secondary metabolites of naturally occurring secondary metabolites.
Course description It gives information about the methods of obtaining secondary metabolites of naturally occurring secondary metabolites.

Course contents
1 Introduction to separation techniques,
2 Preparative chromatography,
3 Distillation and extraction techniques,
4 Preparative uses of column chromatography,
5 Thin layer chromatography,
6 Flash chromatography,
7 Medium pressure liquid chromatography,
8 High pressure liquid chromatography,
9 Gas chromatography,
10 Liquid-liquid extraction,
11 Solid phase extraction, fractional distillation,
12 Molecular distillation and counter-current distillation.
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Learning outcomes of the course unit
1 Natural products have information about the preparative separation techniques
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10

*Contribution level of the course unit to the key learning outcomes
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Number of stars refer to level of contribution from 1 (the least) to 5 (the most)

Planned learning activities, teaching methods and ECTS work load
  Quantity Time (hour) Quantity*Time (hour)
Lectures (face to face teaching) 14 2 28
Study hours out of classroom (study before and after the class) 2 5 10
Homework 2 20 40
Presentation / seminar 0 0 0
Quiz 0 0 0
Preparation for midterm exams 1 10 10
Midterm exams 1 2 2
Project (term paper) 0 0 0
Laboratuar 14 2 28
Field study 0 0 0
Preparation for final exam 3 20 60
Final exam 1 2 2
Research 5 5 25
Total work load     205
ECTS     8.00

Assessment methods and criteria
Evaluation during semester Quantity Percentage
Midterm exam 1 40
Quiz 0 0
Homework 0 0
Semester total   40
Contribution ratio of evaluation during semester to success   40
Contribution ratio of final exam to success   60
General total   100

Recommended and required reading
Textbook No
Additional references Çelebioğlu, S. (1949) Farmakognozi. İstanbul: İstanbul Üniv.Yay.No.421. *Baytop, T. (1986) Farmakognozi Ders Kitabı, Cilt I. İstanbul: İstanbul Üniv.Yay.No.3399. *Baytop, T. (1983) Farmakognozi Ders Kitabı, Cilt II, İstanbul: İstanbul Üniv.Yay.No.2003. *Wallis, T.E. (1967) Textbook of Pharmacognosy. London: J. A.Churchill Ltd.. *Evans, W. C. (2002) Trease and Evans' Pharmacognosy, 15th Ed.. Edinburg, UK: W.B.Saunders. *Tyler, V. E., Brady, L. R., Robbers, J. E. (1988) Pharmacognosy. Philadelphia: Lea Febiger. *Baytop, A. (1991) Bitkisel Drogların Anatomik Yapısı. İstanbul: İstanbul Üniv.Yay.No.3678. *Harborne, J.B. (1984) Phytochemical Methods, 2nd Edition. Chapman and Hall. *Türk Farmakopesi 1974, T.C.Sağlık ve Sosyal Yardım Bakanlığı Sayı:435, Milli Eğitim Basımevi, İstanbul. *British Pharmacopoeia 1998, Volume I- II, The Stationary Office, London, 1998. T*he United States Pharmacopeia (USP24) / The National Formulary (NF19) 2000 , United States Pharmacopeial Convention, Inc.12601 Twinbrook Parkway, Rockville, MD 20852, 1999. *European Pharmacopoeia (EP), 5th Edition, Council of Europe, 67075 Strasbourg Cedex, France, 2005. *Shellard, E.J. (1958) Exercises in the Evaluation of Drugs and Surgical Dressings. London: Pitman Medical Publishing Co.Ltd

Files related to the course unit