Erciyes University - Info Package

Course unit title	Level of course unit	Course unit code	Type of course unit	Semester of course unit	Local credit	ECTS credit	Syllabus
DNA AND CHROMOSOMES	Second cycle	TIB 524		1	6.00	6.00	Print

Description of course unit

Prerequisites and course requisities	None
Language of instruction	Turkish
Coordinator	ASSOC. PROF. DR. NEFİSE NALAN İMAMOĞLU ŞİRVANLI
Lecturer(s)	ASSOC. PROF. DR. NEFİSE NALAN İMAMOĞLU ŞİRVANLI
Teaching assitant(s)	None
Mode of delivery	Course description (interactive), presentations with Power point, question-answer discussion methods are using on theoretical courses
Course objective	The aim of this course is to give students detailed information on the ultrastructure of the interphase nucleus, the structure of DNA, histon proteins, the formation of nucleosome, chromatin, chromatid and chromosomal organisation, heterochromatin and euchromatin, morphology of chromosomes, polyten and lamb brush chromosomes, the structures of centromere, satellite and telomer, and the structure and formation of nucleolus.
Course description	This course includes detailed theoretical information about DNA, chromatin and chromosomes and describes how DNA is packaged to form chromosomes.

Course contents

1	The ultrastructure of interphase nucleus
2	The structure and characteristics of DNA
3	Histon proteins and their characteristics
4	The structure and formation of nucleosome
5	Chromatin structure; Heterochromatin and Euchromatin
6	Packaging of DNA; nucleosome, chromatin, chromatid and chromosomal organisation
7	Morphology of chromosomes and the structures of centromere, satellite, telomere, secondary constriction in chromosomes
8	MID-TERM EXAM
9	Specialized chromosomeş showing the different structures; Polyten and lamb brush chromosomes
10	The structure and formation of Nucleolus
11	Molecular organisation of mitochondrial and chloroplast DNA
12	Satellite DNA; centromeric and telomeric DNA sequences
13	Eukaryotic genomes and repetitive DNA sequences
14	DNA repeats dispersed throughout the genome: SINEs and LINEs
15	Genes and chromosomes
16	FINAL EXAM
17	RESIT EXAM
18
19
20

Learning outcomes of the course unit

1	To be able to describe the main features of DNA
2	To have knowledge about the ultrastructure of the interphase nucleus
3	To be able to understand the structures of nucleosome and chromatin
4	To be able to describe how DNA is packaged to form a chromosome
5	To be able to describe the structure and types of chromosome
6	To be able to explain the structure and formation of nucleolus
7	To have knowledge about the eukaryotic genomes and repetitive DNA sequences
8
9
10

*Contribution level of the course unit to the key learning outcomes

1
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45
Number of stars refer to level of contribution from 1 (the least) to 5 (the most)

Planned learning activities, teaching methods and ECTS work load

	Quantity	Time (hour)	Quantity*Time (hour)
Lectures (face to face teaching)	14	2	28
Study hours out of classroom (study before and after the class)	14	3	42
Homework	0	0	0
Presentation / seminar	1	14	14
Quiz	0	0	0
Preparation for midterm exams	6	4	24
Midterm exams	1	2	2
Project (term paper)	0	0	0
Laboratuar	0	0	0
Field study	0	0	0
Preparation for final exam	8	4	32
Final exam	1	2	2
Research	0	0	0
Total work load			144
ECTS			6.00

Assessment methods and criteria

Evaluation during semester	Quantity	Percentage
Midterm exam	1	40
Quiz	0	0
Homework	0	0
Semester total		40
Contribution ratio of evaluation during semester to success		40
Contribution ratio of final exam to success		60
General total		100

Recommended and required reading

Textbook	Hücre Moleküler Yaklaşım. 3. Baskı, Geoffey M. Cooper, Robert E. Hausman, Çeviri Editörleri; Meral Sakızlı, Neşe Atabey, İzmir Tıp kitapevi, 2006.
Additional references	Moleküler Hücre Biyolojisi,Harvey Lodish, Arnold Berk, Chris A. Kaiser, Monty Krieger, Matthew P. Scott, Anthony Bretscher, Hidde Ploegh, Paul Matsudaira, 6. Baskıdan Çeviri, Çeviri Editörleri: Hikmet Geçkil, Murat Özmen, Özfer Yeşilada, Palme yayıncılık,2011; Moleküler Hücre Biyolojisi, Prof.Dr. Hasan Veysi GÜNEŞ, 2. Baskı, Kaan Kitabevi, 2006; Lecture notes, related articles and websites.

Files related to the course unit