Erciyes University - Info Package

Course unit title	Level of course unit	Course unit code	Type of course unit	Semester of course unit	Local credit	ECTS credit	Syllabus
NUTRIENT MEDICATION INTERACTION	Second cycle	BES 303		5	2.00	2.00	Print

Description of course unit

Prerequisites and course requisities	None
Language of instruction	Turkish
Coordinator	Assist.Prof.Dr. İffet İpek BOŞGELMEZ
Lecturer(s)	Assist.Prof.Dr. İffet İpek BOŞGELMEZ
Teaching assitant(s)	None
Mode of delivery	Face to face. Theoretical and case studies.
Course objective	Improving knowledge of interactions between some drugs and chemicals in the nutrients, applying these knowledge on nutritional program of people under drug treatment.
Course description	Interactions between dietary factors (nutrients and nutrients) and drug or drug groups and other chemicals, which impact bioavailability, requirement and function of nutrients in animals and humans.

Course contents

1	Introduction, basic terminology, pharmacovigilance
2	Terms and definitions related with drug interactions
3	An overview of pharmaceutical, pharmacodynamic, pharmacokinetic drug interactions
4	Fundamentals of pharmacokinetics
5	Pharmacokinetic drug interactions (absorption)
6	Pharmacokinetic drug interactions (distribution)
7	Pharmacokinetic drug interactions (basics of biotransformation)
8	Midterm
9	Pharmacokinetic drug interactions (examples of interactions related with biotransformation)
10	Pharmacokinetic drug interactions (elimination)
11	Complementary and alternative med. and drug interactions
12	Samples and case studies -1
13	Samples and case studies -2
14	Samples and case studies -3
15	Final exam
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17
18
19
20

Learning outcomes of the course unit

1	Improving knowledge of biochemical effect of some used drugs and chemicals on the nutrients, applying of these knowledge on nutritional programme of patients.
2	The importance of absorption (both for drugs and nutrients) during therapy, especially critical impacts for medications applied via oral route will be evaluated.
3	The students will work on interactions at biotransformation level, with special emphasis on inhibitors and inducers of drug metabolizing enzymes (esp. common/important examples).
4	Drug interaction examples encountered during excretion will be understood.
5	The students will deal with food-drug interaction samples and practice on case studies.
6	The students will learn the interactions between drugs and herbal/other products, and the underlying mechanisms.
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8
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10

*Contribution level of the course unit to the key learning outcomes

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5
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45
Number of stars refer to level of contribution from 1 (the least) to 5 (the most)

Planned learning activities, teaching methods and ECTS work load

	Quantity	Time (hour)	Quantity*Time (hour)
Lectures (face to face teaching)	15	2	30
Study hours out of classroom (study before and after the class)	0	0	0
Homework	1	4	4
Presentation / seminar	0	0	0
Quiz	0	0	0
Preparation for midterm exams	1	4	4
Midterm exams	1	1	1
Project (term paper)	0	0	0
Laboratuar	0	0	0
Field study	0	0	0
Preparation for final exam	1	5	5
Final exam	1	1	1
Research	0	0	0
Total work load			45
ECTS			2.00

Assessment methods and criteria

Evaluation during semester	Quantity	Percentage
Midterm exam	1	20
Quiz	0	0
Homework	1	20
Semester total		40
Contribution ratio of evaluation during semester to success		40
Contribution ratio of final exam to success		60
General total		100

Recommended and required reading

Textbook	-
Additional references	1- Choe, JY (2011) Drug Actions and Interactions. McGraw Hill Medical. 2- Dasgupta, A, and Hammett-Stabler, CA (2011) Herbal Supplements: Efficacy, Toxicity, Interactions with Western Drugs, and Effects on Clinical Laboratory Tests. Wiley. 3- Demirezer LÖ (Ed.) (2011) FFD Monografları “Tedavide Kullanılan Bitkiler” Nobel Tıp Kitabevleri, Ankara. 4- Kayaalp, S.O. (Ed.) (2012) Akılcıl Tedavi Yönünden Tıbbi Farmakoloji, Pelikan Yayıncılık, Ankara. 5- Lexicomp (2013) Drug Information Handbook: A Comprehensive Resource for all Clinicians and Healthcare Professionals. Wolter Kluwer Health. 6- Rodrigues, AD (2008) Drug-Drug Interactions. Informa Healthcare. 7- Vural, N (2005) Toksikoloji. Ankara Üniversitesi Eczacılık Fakültesi Yayınları No:73. 8- http://reference.medscape.com/drug-interactionchecker

Files related to the course unit