Course unit title Level of course unit Course unit code Type of course unit Semester of course unit Local credit ECTS credit Syllabus
STRUCTURES AND PROPERTIES OF BIOMOLECULES II Second cycle BİK 502 1 8.00 8.00 Print
   
Description of course unit
Prerequisites and course requisities BIK 501 coded course must be taken.
Language of instruction Turkish
Coordinator PROF. DR. SEMA KADER KÖSE
Lecturer(s) PROF. DR. SEMA KADER KÖSE
Teaching assitant(s) -----------
Mode of delivery Three hours of theoretical lectures per week will be held.
Course objective The objective is to teach the student an overview of the physical-chemical basis for the structures of biological molecules:Lipids and carbohydrates; their structure-function relationships; cell membranes, structure and functions, and also functional significance of their structures.
Course description Only postgraduate students are accepted for the course. Students are expected to attend all scheduled classroom.

Course contents
1 Lipids, general properties and classification.
2 Fatty acids, general properties and classification.
3 Structure of complex lipids: phospholipids, ether lipids, sphingolipids.
4 Sterols and cholesterol.
5 Lipids with specific biological activity.
6 Purification of lipids.
7 Membrane structures, lipids as component of membranes.
8 Membrane structures, proteins as component of membranes.
9 Carbohydrates, general properties and classification.
10 Monosaccharides , structures, properties and reactions.
11 –Disaccharides, structures and properties.
12 Glycosaminoglycans and proteoglycans.
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Learning outcomes of the course unit
1 Recognize the saturated/unsaturated and essential fatty acids and will have information about clinical significance.
2 Learn the basic lipid structures such as triglycerides, phospholipids, sphingolipids and cholesterol, and their functions in the organism.
3 Learn lipid composition of biomembranes, and that membranes are dynamic structures according to "fluid-mosaic model".
4 Learn chromatographic methods used in purification of the lipids and fatty acids found in biological material.
5 Recognize the lipids which have the specific biological activity, such as bile acids, steroid hormones, fat-soluble vitamins (ADEK), quinones, dolichols, prostaglandins, thromboxanes and leukotrienes, and will have information about intracellular messengers derived from lipids.
6 Know the lipoprotein structures, such as HDL, LDL, VLDL and chylomicrons, and also their functions and how to synthesize in organism; in addition, will have information about hyperlipidemia types, according to "Fredrickson classification" and their clinical findings.
7 Learn the structures, properties, and reactions of monosaccharides, such as glucose, fructose and galactose, and disaccharides, such as maltose, sucrose and lactose, and oligosaccharides.
8 Recognize the structures of homopolysaccharides, such as starch, glycogen, dextran and ?-glucan, and glycosaminoglycans such as hyaluronic acid and chondroitin sulfate, and also proteoglycans and glycoproteins, and learn their functions in the organism.
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*Contribution level of the course unit to the key learning outcomes
1 Using knowledge of obstetrics and gynecology at high level for building hypothesis, solving and developing them.
2 Creating an innovative way of thinking in the field of obstetrics and gynecology for scientific methods, designs or applications or implementing /applying a known idea for the methodsand designsin the field of obstetrics and gynecology
3 Designing, applying and finalizing an obstetrics and gynecology study using suitable Technologies
4 Accessing the latest information in the field of obstetrics and gynecology and evaluating them in a systematic manner
5 Presenting and publishing the results of his academic studies in national and international academic platforms.
6 Knowing the importance of ethical principles and ethics committees for individuals and for the society.
7 Evaluating the obstetrics and gynecology -related information in a criticizing manner
8 Having the skills of oral and written communication, collaboration, defending his opinions; for working at his own field, the other fields of veterinary medicine, scientific and social communities
9 Leadership ability to resolve the problems in novel and interdisciplinary environments when necessary
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Number of stars refer to level of contribution from 1 (the least) to 5 (the most)

Planned learning activities, teaching methods and ECTS work load
  Quantity Time (hour) Quantity*Time (hour)
Lectures (face to face teaching) 14 3 42
Study hours out of classroom (study before and after the class) 14 3 42
Homework 0 0 0
Presentation / seminar 1 10 10
Quiz 0 0 0
Preparation for midterm exams 1 10 10
Midterm exams 1 2 2
Project (term paper) 0 0 0
Laboratuar 0 0 0
Field study 0 0 0
Preparation for final exam 1 20 20
Final exam 1 2 2
Research 14 5 70
Total work load     198
ECTS     8.00

Assessment methods and criteria
Evaluation during semester Quantity Percentage
Midterm exam 1 40
Quiz 0 0
Homework 0 0
Semester total   40
Contribution ratio of evaluation during semester to success   40
Contribution ratio of final exam to success   60
General total   100

Recommended and required reading
Textbook Power Point files prepared by lecturer. Nelson DL, Cox MM. Lehninger Principles of Biochemistry (3rd ed), Worth Publishers, New York, 2000.
Additional references Berg JM, Tymoczko JL, Stryer L. Biochemistry. 5th Edition, W. H. Freeman and Company, New York, 2002.

Files related to the course unit