Erciyes University - Info Package

Course unit title	Level of course unit	Course unit code	Type of course unit	Semester of course unit	Local credit	ECTS credit	Syllabus
FUNDAMENTALS OF ENZYMOLOGY	Second cycle	KİMS371		5	3.00	3.00	Print

Description of course unit

Prerequisites and course requisities	-
Language of instruction	Turkish
Coordinator	Yrd.Doç.Dr.Nalan ÖZDEMİR
Lecturer(s)	Yrd.Doç.Dr.Nalan ÖZDEMİR
Teaching assitant(s)	-
Mode of delivery	Face to Face
Course objective	Introduction to enzymes and enzyme kinetics and understanding of the enzyme structures and functions.
Course description	General properties of enzymes, differences of enzymes from chemical catalysts, chemical structure of enzymes, cofactors and coenzymes, biosynthesis enzymes, nomenclature and classification of enzymes, oxidoreductases, transferases, hydrolases, lyases, isomerases , ligases, the methods of enzyme activity, the factors acting on the enzyme activities,enzyme kinetics: Michaelis - Menten, Line weaver - Burk curves, the specificity of the enzymes, allosteric enzymes. activators and inhibitors, competitive inhibition, noncompetitive inhibition, objective and strategy of the purification of enzyme, immobilization of the enzymes.

Course contents

1	General properties of enzymes
2	Differences of enzymes from chemical catalysts
3	Chemical structure of enzymes, aminoacids and structure of proteins
4	Cofactors and coenzymes, biosynthesis enzymes
5	Nomenclature and classification of enzymes, oxidoreductases, transferases, hydrolases, lyases, isomerases , ligases
6	The methods of enzyme activity, the factors acting on the enzyme activit
7	Midterm exam
8	Enzyme kinetics: Michaelis - Menten, Line weaver - Burk curves
9	Enzyme kinetics: Michaelis - Menten, Line weaver - Burk curves
10	The specificity of the enzymes, allosteric enzymes
11	Activators and inhibitors
12	Competitive inhibition, noncompetitive inhibition
13	Objective and strategy of the purification of enzyme
14	Immobilization of the enzymes
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Learning outcomes of the course unit

1	Learning general properties of the enzyme
2	Learning the differences of enzymes as biocatalysts from chemical catalysts
3	Understanding the chemical structure of enzymes
4	Learning the nomenclature and clasification of the enzymes
5	Understanding the enzyme kinetics
6	Learning the methods of enzyme activities
7	Learning the enzyme inhibitions
8	Understanding the objectives of enzyme purification
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10

*Contribution level of the course unit to the key learning outcomes

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Number of stars refer to level of contribution from 1 (the least) to 5 (the most)

Planned learning activities, teaching methods and ECTS work load

	Quantity	Time (hour)	Quantity*Time (hour)
Lectures (face to face teaching)	14	2	28
Study hours out of classroom (study before and after the class)	14	2	28
Homework	0	0	0
Presentation / seminar	0	0	0
Quiz	0	0	0
Preparation for midterm exams	1	2	2
Midterm exams	1	2	2
Project (term paper)	0	0	0
Laboratuar	0	0	0
Field study	0	0	0
Preparation for final exam	0	0	0
Final exam	1	2	2
Research	0	0	0
Total work load			62
ECTS			2.00

Assessment methods and criteria

Evaluation during semester	Quantity	Percentage
Midterm exam	1	40
Quiz	0	0
Homework	0	0
Semester total		40
Contribution ratio of evaluation during semester to success		40
Contribution ratio of final exam to success		60
General total		100

Recommended and required reading

Textbook
Additional references

Files related to the course unit