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Description of epigenetics and known epicenetic regulation mechanisma.
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Forms of DNA, aspects and conditionsfort he formotion of these forms.. Z DNA, its aspects and role in gene regulation.
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Histon acetilation, effects, protein systems have rol in histon acetylation. Remodeling of DNA
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The neaning of Methylation. Protein, RNA and DNA methylation, enzymes playing role, comparison of procaryota and eucaryota. Relation with restriction endonucleases, e.t.c..
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In human and other mammalia. And other species. DNA methylation, Methylation- demethylation,
- hiper and -hipo methylation,, tissue specific heredity proportions and pattern.
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CpG islands, methyl-Cytosine and resemblance to timine and effects. Comparison of the gene promoters regulated on methylation and other mechanisms
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Results of changes in specific methylation pattern of species or tissue.
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Description, origin, functions and laboratory use of rRestriction enzymes. Hpa II ve Msp I examples, and searching whole genom DNA methylation ,
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Old and new methods: Comparison
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Genomic imprinting, X chromatin, natural and unnatural, single gene methylations and their results.
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Unnatural demetilation and hypermethylation and their association with disseases.
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Usage of DNA hipomethylation in some disseases via hemoglobin gene family example..
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Article discussion
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General discussion
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DOLDURULACAK
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