Erciyes University - Info Package

Course unit title	Level of course unit	Course unit code	Type of course unit	Semester of course unit	Local credit	ECTS credit	Syllabus
MOLECULAR DIAGNOSTIC METHODS	Third cycle	BİK 616		1	8.00	8.00	Print

Description of course unit

Prerequisites and course requisities	None
Language of instruction	Turkish
Coordinator	Prof.Dr.Sabahattin Muhtaroğlu
Lecturer(s)	Prof.Dr.Sabahattin Muhtaroğlu
Teaching assitant(s)	None
Mode of delivery	Threotical-pratical application
Course objective	1.Identify the important parameters in the design of a laboratory to conduct the most commonly used molecular diagnostic procedures.. 2. Identify the important parameters in the design of a quality system for molecular analyses. 3. Become proficient with the techniques required to perform the most commonly used molecular diagnostics protocols. 4. Identify the components of a well-controlled diagnostic test. 5. Use critical thinking skills to trouble shoot problems as they occur and determine possible causes.
Course description	Molecular diagnostic tests detect specific sequences in DNA or RNA that may or may not be associated with disease, including single nucleotide polymorphism (SNP), deletions, rearrangements, insertions and others. Clinical applications can be found in at least six general areas: infectious diseases; oncology; pharmacogenomics; genetic disease screening; human leukocyte antigen typing; and coagulation.

Course contents

1	Molecular and non-molecular methods
2	Method used in molecular biology
3	İsolation and analysis of DNA
4	İsolation and analysis of RNA
5	Ampliphication of DNA by chain polymease reaction(PCR)
6	Types of PCR
7	Nucleic acid hybridization methods
8	İsolation and purification of proteins
9	Genomics and proteomics
10	molecular methods and autamation
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Learning outcomes of the course unit

1	Apply knowledge of cellular structure and function, especially DNA and RNA, to molecular diagnostic procedures.
2	Gain a thorough working knowledge of nucleic acid extraction, resolution and detection.
3	Gain a solid foundation in the most commonly utilized molecular diagnostic testing protocols.
4	Apply the knowledge of molecular testing to the most commonly performed applications in the clinical laboratory such as: nucleic acid extraction, resolution and detection, analysis and characterization of nucleic acids and proteins, nucleic acid amplification and DNA sequencing.
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*Contribution level of the course unit to the key learning outcomes

1	Obtain basic knowledge and competence for researching and studying in the field of Turkish language and literature.
2	Evaluate the concepts and theories in the field of Turkish language and literature with a scientific methods
3	Realise the historical development and change of Turkish language and literature from its beginning to the present time.
4	Execute advanced searches and studies in Turkish language and literature subjects independently.
5	Gain the competence and knowledge of reading, writing and understanding the texts written in Ottoman Turkish.
6	Use Turkish correctly and well.
7	Recognize verbal-written products and sources of Turkish folk culture and literature.
8	Develop their sensibility and tastes in language and literature fields.
9	Comprehend historical and contemporary Turkish dialect and vernaculars with the help of Göktürk, Uygur and Kiril alphabets.
10	Control professional terminology.
11	Access knowledge and documents related to Turkish language and literature with the help of libraries and the internet.
12	Own the competence of seeing problems related to discipline, evaluating with a critical outlook and producing solutions.
13	Develop suggestion based on solving the problems faced related to field.
14	Determine the religious, philosophical and artistic movements Turkish language is affected and their traces.
15	Interdisciplinary perspective and can be assessed.
16	Make compilations in folklore field.
17	Realises the need of life-long learning.
18	Own systematic thinking, capability and capacity.
19	Own scientific and professional ethic and responsibility
20	Own a critical understanding about the word they live in, the society they belong to and themselves.
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Number of stars refer to level of contribution from 1 (the least) to 5 (the most)

Planned learning activities, teaching methods and ECTS work load

	Quantity	Time (hour)	Quantity*Time (hour)
Lectures (face to face teaching)	14	3	42
Study hours out of classroom (study before and after the class)	14	4	56
Homework	6	3	18
Presentation / seminar	6	1	6
Quiz	4	1	4
Preparation for midterm exams	12	2	24
Midterm exams	2	1	2
Project (term paper)	0	0	0
Laboratuar	6	2	12
Field study	0	0	0
Preparation for final exam	10	2	20
Final exam	1	2	2
Research	5	2	10
Total work load			196
ECTS			8.00

Assessment methods and criteria

Evaluation during semester	Quantity	Percentage
Midterm exam	2	20
Quiz	2	10
Homework	0	0
Semester total		30
Contribution ratio of evaluation during semester to success		60
Contribution ratio of final exam to success		40
General total		100

Recommended and required reading

Textbook
Additional references

Files related to the course unit

About CIP

About the Course

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