Course unit title Level of course unit Course unit code Type of course unit Semester of course unit Local credit ECTS credit Syllabus
ANTIBIOTIC SUSCEPTIBILITY TESTING Third cycle DMIK603 1 6.00 6.00 Print
   
Description of course unit
Prerequisites and course requisities Basic Bacteriology
Language of instruction English
Coordinator Prof. Duygu Perçin Renders
Lecturer(s) Prof. Duygu Perçin Renders
Teaching assitant(s) -
Mode of delivery Theoretical and practical lessons
Course objective The goals of this course are to teach action mechanisms of antibiotics, resistance mechanisms to certain antibiotics, antibiotic susceptibility testing, synergy tests, and quality control in susceptibility testing
Course description Action mechanisms of antibiotics, resistance mechanisms to certain antibiotics, antibiotic susceptibility testing, synergy tests, and quality control in susceptibility testing

Course contents
1 Beta-lactam antibiotics
2 Resistance mechanisms to beta-lactams
3 Quinolones and resistance mechanisms
4 Glycopeptides and resistance mechanisms
5 Aminoglycosides and resistance mechanisms
6 MLSB group antibitics and resistance mechanisms
7 Other antimicrobials
8 Diffusion tests
9 Dilution tests
10 Bactericidal activity tests
11 Time-kill assay
12 Synergy tests
13 Quality control in susceptibility testing
14 Interpretation of susceptibility tests
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Learning outcomes of the course unit
1 The students will be able to perform susceptibility tests, evaluate the results and interpret the resistance mechanisms
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*Contribution level of the course unit to the key learning outcomes
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Number of stars refer to level of contribution from 1 (the least) to 5 (the most)

Planned learning activities, teaching methods and ECTS work load
  Quantity Time (hour) Quantity*Time (hour)
Lectures (face to face teaching) 15 2 30
Study hours out of classroom (study before and after the class) 15 2 30
Homework 2 5 10
Presentation / seminar 1 10 10
Quiz 1 1 1
Preparation for midterm exams 1 10 10
Midterm exams 1 1 1
Project (term paper) 1 10 10
Laboratuar 15 1 15
Field study 0 0 0
Preparation for final exam 1 15 15
Final exam 1 1 1
Research 1 20 20
Total work load     153
ECTS     6.00

Assessment methods and criteria
Evaluation during semester Quantity Percentage
Midterm exam 1 40
Quiz 1 20
Homework 1 40
Semester total   100
Contribution ratio of evaluation during semester to success   40
Contribution ratio of final exam to success   60
General total   100

Recommended and required reading
Textbook 1. Manual of Clinical Microbiology, Versalovic J, Carroll KC, Funke G, Jorgensen JH, Landry ML, Warnock DW (editors) 10th ed, Vol:1, ASM Press, Washington DC, 2011. 2. Topley and Wilson’s Microbiology and Microbial Infections. Borriello SP, Murray PR, Funke G (editors), 10th edition, Vol 1-2, Edward Arnold Publishers, UK, 2005. 3. Antibiotics in laboratory medicine, 3th ed, In: Lorian V editor.. The Williams & Wilkins Co, Baltimore, USA. 1991.
Additional references 1. Clinical and Laboratory Standard Institute. Methods for Dilution Antimicrobial Susceptibility Tests for Bacteria That Grow Aerobically; Approved Standart-Eight Edition. CLSI document M07-A8(ISBN 1-56238-689-1).Clinical and Laboratory Standard Institute, 940 West Valley Road, Suite 1400, Wayne, Pennsylvania 19087-1898 USA, 2009 2. CLSI. Performance Standards for Antimicrobial Susceptibility Testing; Twenty-First Informational Supplement. CLSI document M100-S21. Wayne, PA: Clinical and Laboratory Standards Institute; 2011

Files related to the course unit